STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ece1Endothelin-converting enzyme 1. (752 aa)    
Predicted Functional Partners:
edn1
Endothelin 1.
     
 0.957
edn3b
Endothelin 3b.
      
 0.862
ednraa
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.860
Edn3
END domain-containing protein.
      
 0.841
nrtn
Neurturin.
      
 0.668
ece2a
Endothelin-converting enzyme 2a.
      
 0.666
ednrba
Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.
      
 0.644
luzp1
Leucine zipper protein 1.
      
 0.644
ide
Novel protein similar to H.sapiens IDE, insulin-degrading enzyme (IDE, zgc:162603); Belongs to the peptidase M16 family.
      
 0.644
phox2bb
Paired-like homeobox 2Bb.
      
 0.622
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.