STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
syn1Synapsin I. (670 aa)    
Predicted Functional Partners:
syt1a
Synaptotagmin Ia.
   
 0.904
snap25a
Synaptosomal-associated protein 25-A; May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion; Belongs to the SNAP-25 family.
   
 0.898
dlg4
Disks large homolog 4; Plays a role in synapse assembly and function. Plays a role in synaptic plasticity.
   
  
 0.864
rab3ab
RAB3A, member RAS oncogene family, b.
   
 0.850
vamp2
Vesicle-associated membrane protein 2.
   
 0.842
stx1a
Syntaxin 1A (brain); Belongs to the syntaxin family.
     
 0.820
syt12
Similar to synaptotagmin XII.
   
 
 0.766
gphnb
Gephyrin2 isoform.
      
 0.737
gphna
Gephyrin a.
      
 0.737
acta1b
Actin alpha 1, skeletal muscle b.
    
 
 0.735
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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