node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ISCU | abcb7 | ENSDARP00000051606 | ENSDARP00000085602 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 0.870 |
ISCU | fech | ENSDARP00000051606 | ENSDARP00000125028 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.868 |
ISCU | fxn | ENSDARP00000051606 | ENSDARP00000115873 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Frataxin. | 0.998 |
ISCU | iba57 | ENSDARP00000051606 | ENSDARP00000055617 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Putative transferase CAF17 homolog, mitochondrial; Required for normal heme biosynthesis. | 0.883 |
ISCU | lyrm4 | ENSDARP00000051606 | ENSDARP00000103510 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis. | 0.989 |
ISCU | lyrm4-2 | ENSDARP00000051606 | ENSDARP00000147532 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Si:ch211-152c8.4; Belongs to the complex I LYR family. | 0.948 |
ISCU | nfs1 | ENSDARP00000051606 | ENSDARP00000084180 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | NFS1 nitrogen fixation 1 (S. cerevisiae). | 0.999 |
ISCU | nfu1 | ENSDARP00000051606 | ENSDARP00000114381 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae). | 0.959 |
ISCU | scly | ENSDARP00000051606 | ENSDARP00000099679 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Selenocysteine lyase. | 0.985 |
ISCU | slc25a37 | ENSDARP00000051606 | ENSDARP00000090636 | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Mitoferrin-1; Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme. | 0.738 |
abcb7 | ISCU | ENSDARP00000085602 | ENSDARP00000051606 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Si:ch211-191d15.2; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.870 |
abcb7 | fech | ENSDARP00000085602 | ENSDARP00000125028 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.958 |
abcb7 | fxn | ENSDARP00000085602 | ENSDARP00000115873 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Frataxin. | 0.948 |
abcb7 | iba57 | ENSDARP00000085602 | ENSDARP00000055617 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Putative transferase CAF17 homolog, mitochondrial; Required for normal heme biosynthesis. | 0.890 |
abcb7 | lyrm4 | ENSDARP00000085602 | ENSDARP00000103510 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis. | 0.855 |
abcb7 | lyrm4-2 | ENSDARP00000085602 | ENSDARP00000147532 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Si:ch211-152c8.4; Belongs to the complex I LYR family. | 0.542 |
abcb7 | nfs1 | ENSDARP00000085602 | ENSDARP00000084180 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | NFS1 nitrogen fixation 1 (S. cerevisiae). | 0.950 |
abcb7 | nfu1 | ENSDARP00000085602 | ENSDARP00000114381 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae). | 0.817 |
abcb7 | scly | ENSDARP00000085602 | ENSDARP00000099679 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Selenocysteine lyase. | 0.551 |
abcb7 | slc25a37 | ENSDARP00000085602 | ENSDARP00000090636 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Mitoferrin-1; Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme. | 0.955 |