STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem236Transmembrane protein 236. (350 aa)    
Predicted Functional Partners:
ift80
Intraflagellar transport 80 homolog (Chlamydomonas).
      
 0.589
prpf6
PRP6 pre-mRNA-processing factor 6 homolog (S. cerevisiae).
      
 0.576
zfyve26
Zinc finger, FYVE domain-containing 26.
      
 0.527
iqsec3a
IQ motif and Sec7 domain ArfGEF 3a.
      
 0.448
iqsec3b
IQ motif and Sec7 domain ArfGEF 3b.
      
 0.448
lrrc14b
Leucine-rich repeat-containing protein 14B; Belongs to the PRAME family. LRRC14 subfamily.
      
 0.441
igsf5b
Immunoglobulin superfamily, member 5b.
      
 0.430
igsf5a
Immunoglobulin superfamily, member 5a.
      
 0.430
mycbp2
E3 ubiquitin-protein ligase MYCBP2; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (By similarity). Plays a key role in neural development, probabl [...]
      
 0.414
slc10a7
Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix (By similarity). Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis (By similarity). Does not show transport activity towards bile acids or steroid sulfates.
      
 0.412
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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