node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ZNF335 | ankle2 | ENSDARP00000151883 | ENSDARP00000117092 | Si:ch211-269m15.3. | Ankyrin repeat and LEM domain-containing 2. | 0.824 |
ZNF335 | cenpj | ENSDARP00000151883 | ENSDARP00000155698 | Si:ch211-269m15.3. | Centromere protein J. | 0.732 |
ZNF335 | cep135 | ENSDARP00000151883 | ENSDARP00000035272 | Si:ch211-269m15.3. | Centrosomal protein of 135 kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for cep250 at the centriole (By similarity). Belongs to the CEP135/TSGA10 family. | 0.749 |
ankle2 | ZNF335 | ENSDARP00000117092 | ENSDARP00000151883 | Ankyrin repeat and LEM domain-containing 2. | Si:ch211-269m15.3. | 0.824 |
ankle2 | banf1 | ENSDARP00000117092 | ENSDARP00000053793 | Ankyrin repeat and LEM domain-containing 2. | Barrier-to-autointegration factor; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity). | 0.782 |
ankle2 | cenpj | ENSDARP00000117092 | ENSDARP00000155698 | Ankyrin repeat and LEM domain-containing 2. | Centromere protein J. | 0.777 |
ankle2 | cep135 | ENSDARP00000117092 | ENSDARP00000035272 | Ankyrin repeat and LEM domain-containing 2. | Centrosomal protein of 135 kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for cep250 at the centriole (By similarity). Belongs to the CEP135/TSGA10 family. | 0.769 |
ankle2 | rabggtb | ENSDARP00000117092 | ENSDARP00000090020 | Ankyrin repeat and LEM domain-containing 2. | Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. | 0.717 |
ankle2 | sirt2 | ENSDARP00000117092 | ENSDARP00000003412 | Ankyrin repeat and LEM domain-containing 2. | NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] | 0.785 |
ankle2 | thg1l | ENSDARP00000117092 | ENSDARP00000055960 | Ankyrin repeat and LEM domain-containing 2. | tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. | 0.744 |
ankle2 | tm2d3 | ENSDARP00000117092 | ENSDARP00000122047 | Ankyrin repeat and LEM domain-containing 2. | TM2 domain-containing protein 3. | 0.748 |
ankle2 | vrk1 | ENSDARP00000117092 | ENSDARP00000045990 | Ankyrin repeat and LEM domain-containing 2. | Serine/threonine-protein kinase VRK1; Serine/threonine kinase involved in Golgi disassembly during the cell cycle; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily. | 0.922 |
ankle2 | vrk2 | ENSDARP00000117092 | ENSDARP00000038349 | Ankyrin repeat and LEM domain-containing 2. | VRK serine/threonine kinase 2. | 0.905 |
banf1 | ankle2 | ENSDARP00000053793 | ENSDARP00000117092 | Barrier-to-autointegration factor; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity). | Ankyrin repeat and LEM domain-containing 2. | 0.782 |
banf1 | vrk1 | ENSDARP00000053793 | ENSDARP00000045990 | Barrier-to-autointegration factor; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity). | Serine/threonine-protein kinase VRK1; Serine/threonine kinase involved in Golgi disassembly during the cell cycle; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily. | 0.794 |
banf1 | vrk2 | ENSDARP00000053793 | ENSDARP00000038349 | Barrier-to-autointegration factor; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity). | VRK serine/threonine kinase 2. | 0.706 |
cenpj | ZNF335 | ENSDARP00000155698 | ENSDARP00000151883 | Centromere protein J. | Si:ch211-269m15.3. | 0.732 |
cenpj | ankle2 | ENSDARP00000155698 | ENSDARP00000117092 | Centromere protein J. | Ankyrin repeat and LEM domain-containing 2. | 0.777 |
cenpj | cep135 | ENSDARP00000155698 | ENSDARP00000035272 | Centromere protein J. | Centrosomal protein of 135 kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for cep250 at the centriole (By similarity). Belongs to the CEP135/TSGA10 family. | 0.982 |
cep135 | ZNF335 | ENSDARP00000035272 | ENSDARP00000151883 | Centrosomal protein of 135 kDa; Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for cep250 at the centriole (By similarity). Belongs to the CEP135/TSGA10 family. | Si:ch211-269m15.3. | 0.749 |