STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gps2G protein pathway suppressor 2. (361 aa)    
Predicted Functional Partners:
hdac3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (By similarity). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May play a role in the regulation of the circadian clock in a deacetylase activity-independent manner (By similarity).
   
 
 0.874
taf9
TAF9 RNA polymerase II, TATA box-binding protein (TBP)-associated factor.
   
 
 0.803
taf12
TAF12 RNA polymerase II, TATA box-binding protein (TBP)-associated factor.
   
 
 0.795
tada3l
Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context (By similarity); Belongs to the NGG1 family.
    
 
 0.786
taf10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
   
 
 0.780
trrap
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.765
supt3h
SPT3 homolog, SAGA and STAGA complex component.
    
 
 0.754
dlg4b
Discs, large homolog 4b (Drosophila); Belongs to the MAGUK family.
      
 0.721
sgf29
SAGA complex-associated factor 29.
   
 
 0.711
ccni2
Cyclin I family, member 2; Belongs to the cyclin family.
      
 0.679
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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