STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grhprbGlyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (361 aa)    
Predicted Functional Partners:
agxtb
Serine--pyruvate aminotransferase.
  
 
 0.990
hoga1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline.
  
 0.988
agxta
Serine--pyruvate aminotransferase.
  
 
 0.982
glyctk
Glycerate kinase; Belongs to the glycerate kinase type-2 family.
 
 
 0.973
hao2
Hydroxyacid oxidase 2 (long chain).
  
 
 0.956
hao1
Hydroxyacid oxidase (glycolate oxidase) 1.
  
 
 0.951
hyi
Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.
  
 
 0.929
glo1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.924
pgp
Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.923
grhpra
Novel protein similar to human glyoxylate reductase/hydroxypyruvate reductase (GRHPR); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
0.904
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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