STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppp4r4Protein phosphatase 4, regulatory subunit 4. (875 aa)    
Predicted Functional Partners:
bphl
Biphenyl hydrolase like.
    
 
 0.860
ptpa
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 
 0.753
aven
Apoptosis, caspase activation inhibitor.
      
 0.743
rab12
RAB12, member RAS oncogene family.
      
 0.743
hgsnat
Heparan-alpha-glucosaminide N-acetyltransferase.
      
 0.719
sh2d1aa
SH2 domain-containing 1A duplicate a.
    
 
 0.719
ppp2ca
Serine/threonine-protein phosphatase.
   
 
 0.689
rer1
Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
   
  
 0.676
ssr4
Signal sequence receptor, delta.
      
 0.669
ccdc22
Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity).
      
 0.664
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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