STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcdh1aProtocadherin 1a. (1190 aa)    
Predicted Functional Partners:
pcdh1g18
Protocadherin 1 gamma 18.
      
 0.669
cadm2a
Cell adhesion molecule 2a.
    
 
 0.652
cx23
Gap junction epsilon-1 protein; Has significant hemichannel activity. However, has only low- efficiency gap junction activity and probably does not function as a gap junction channel in vivo; Belongs to the connexin family. Beta-type (group I) subfamily.
      
 0.648
gja8b
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.561
cdh18a
Cadherin 18, type 2a.
      
 0.479
ormdl3
ORM1-like protein 3; Negative regulator of sphingolipid synthesis; Belongs to the ORM family.
   
  
 0.455
cadm4
Cell adhesion molecule 4.
   
 
 0.424
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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