STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dlx4aHomeobox protein Dlx4a. (250 aa)    
Predicted Functional Partners:
E7FAA1_DANRE
Si:ch211-157c3.4.
      
 0.743
pou3f3a
POU domain, class 3, transcription factor 3-A; Transcription factor that may play important roles in patterning the embryonic brain.
   
 
 0.567
cax1
Type II CAX cation/proton exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.546
hand2
Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis.
   
  
 0.521
edn1
Endothelin 1.
   
  
 0.486
grn2
Granulin 2.
    
 
 0.476
ednraa
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.452
hmgb3b
High mobility group box 3b.
    
 
 0.411
dcaf7
Ddb1 and cul4-associated factor 7.
   
  
 0.401
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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