STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prkcgProtein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (654 aa)    
Predicted Functional Partners:
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.917
plce1
Phospholipase C, epsilon 1.
   
 
 0.908
plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 0.905
plcg1
Phosphoinositide phospholipase C.
   
 0.905
raf1b
Raf-1 proto-oncogene, serine/threonine kinase b.
    
 
0.903
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 
0.903
ptk2ab
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
0.901
sphk2
Sphingosine kinase 2.
     
  0.900
SPHK1
Sphingosine kinase 1.
     
  0.900
LOC101886286
PH domain-containing protein.
   
  
 0.833
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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