STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxcr1bGlutaredoxin and cysteine-rich domain-containing 1 b. (148 aa)    
Predicted Functional Partners:
ush1c
Usher syndrome 1C (Autosomal recessive, severe).
      
 0.868
ush1ga
Usher syndrome 1Ga (autosomal recessive).
      
 0.759
cdh23
Cadherin-related 23.
      
 0.751
cdh23-2
Cadherin-related 23.
      
 0.739
mamdc2a
MAM domain-containing 2a.
      
 0.719
loxhd1a
Lipoxygenase homology domains 1a.
      
 0.682
gipc3
GIPC PDZ domain-containing family, member 3.
   
  
 0.677
slc52a3
Solute carrier family 52, riboflavin transporter, member 3-A; Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
      
 0.664
adgrv1
Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system.
   
  
 0.644
txndc17
Thioredoxin domain-containing protein 17; Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity); Belongs to the thioredoxin family.
      
 0.644
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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