STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyglAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa)    
Predicted Functional Partners:
pgm1
Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.
  
 
 0.906
gys2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
  
 
 0.894
agla
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a.
  
 0.866
pgm5
Phosphoglucomutase 5.
  
 
 0.863
gbe1a
Glucan (1,4-alpha-),-branching enzyme 1a.
  
 0.856
gbe1b
Glucan (1,4-alpha-),-branching enzyme 1b.
  
 0.856
otc
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
 
 0.849
aglb
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b.
  
 0.834
pgm3
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
  
 
 0.807
ENSDARP00000143879
Uncharacterized protein.
  
 0.800
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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