STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pacsin2Protein kinase C and casein kinase substrate in neurons 2. (490 aa)    
Predicted Functional Partners:
ehd2b
EH-domain-containing 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.764
pear1
Platelet endothelial aggregation receptor 1.
      
 0.744
zmiz2
Zinc finger, MIZ-type-containing 2.
      
 0.743
mpped1
Metallophosphoesterase domain-containing 1.
   
  
 0.673
F1R8V5_DANRE
Si:ch211-193c2.2.
      
 0.669
eps15
Epidermal growth factor receptor pathway substrate 15.
      
 0.663
cav2
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
      
 0.656
tubb1
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
      
 0.615
bin2a
Bridging integrator 2a.
      
 0.606
fcho2
F-BAR domain only protein 2; May function in an early step of clathrin-mediated endocytosis.
     
 0.606
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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