STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnajb12bDnaJ heat shock protein family (Hsp40) member B12b. (369 aa)    
Predicted Functional Partners:
dnajc28
DnaJ (Hsp40) homolog, subfamily C, member 28.
      
 0.811
dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24.
   
  
 0.705
dnajc19
Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).
      
 0.686
hspa9
Heat shock protein 9; Belongs to the heat shock protein 70 family.
 
 0.683
hspa5
Immunoglobulin binding protein; Belongs to the heat shock protein 70 family.
 
 0.682
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
   
 
 0.682
hsph1
Heat shock 105/110 protein 1.
 
 0.673
hspa14
Heat shock 70 kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding- competent state.
 
 0.667
dnajc2
DnaJ homolog subfamily C member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription ac [...]
   
 
 0.654
hsp70l
Novel protein similar to heat shock cognate 70-kd protein; Belongs to the heat shock protein 70 family.
 
 0.645
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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