STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col4a3Collagen, type IV, alpha 3. (1684 aa)    
Predicted Functional Partners:
col5a1
Procollagen, type V, alpha 1.
  
  
0.828
itga3b
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
   
 0.775
itgb6
Integrin beta; Belongs to the integrin beta chain family.
    
 0.721
itga3a
Integrin, alpha 3a; Belongs to the integrin alpha chain family.
    
 0.712
itga2.2
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.
     
 0.694
itga5
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family.
    
 0.685
itgb3a
Integrin beta; Belongs to the integrin beta chain family.
   
 0.669
itgb3b
Integrin beta; Belongs to the integrin beta chain family.
   
 0.669
itgb1a
Integrin beta; Belongs to the integrin beta chain family.
   
 0.669
itgb4
Integrin beta.
    
 0.667
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]