STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
baz1a-2Bromodomain adjacent to zinc finger domain, 1A. (582 aa)    
Predicted Functional Partners:
pole3
Polymerase (DNA directed), epsilon 3 (p17 subunit).
   
 0.992
chrac1
Chromatin accessibility complex subunit 1.
   
 0.978
smarca5
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 5.
   
 
 0.952
smarca1
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 1.
   
 
 0.839
hells
Helicase, lymphoid-specific.
   
 
 0.762
eapp
E2f-associated phosphoprotein.
   
  
 0.720
baz1b
Tyrosine-protein kinase BAZ1B; Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates [...]
    
0.698
dcxr
Dicarbonyl/L-xylulose reductase.
      
 0.670
sptssa
Serine palmitoyltransferase small subunit A; Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference (By similarity). Belongs to the SPTSS family. SPTSSA subfamily.
      
 0.669
bptf
Bromodomain PHD finger transcription factor.
   
 
0.641
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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