STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fgd5aFYVE, RhoGEF and PH domain-containing 5a. (1473 aa)    
Predicted Functional Partners:
arhgef9b
Cdc42 guanine nucleotide exchange factor (GEF) 9b.
      
 0.569
tpcn1
Two pore segment channel 1.
   
  
 0.545
cdc42ep2
CDC42 effector protein (Rho GTPase-binding) 2.
      
 0.544
plekhg5a
Pleckstrin homology domain-containing, family G (with RhoGef domain) member 5a.
      
 0.540
kcnj4
Uncharacterized protein.
      
 0.532
ldb2a
LIM domain-binding 2a.
   
  
 0.492
cass4
Cas scaffold protein family member 4.
    
 
 0.490
rnf144b
RBR-type E3 ubiquitin transferase.
      
 0.486
ctnnal1
Catenin (cadherin-associated protein), alpha-like 1.
      
 0.484
ubxn10
UBX domain-containing protein 10; Required for ciliogenesis. Acts as a tethering factor that facilitates recruitment of vcp/p97 to the intraflagellar transport complex B (IFT-B) in cilia (By similarity).
      
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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