STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col12a1aCollagen, type XII, alpha 1a. (2975 aa)    
Predicted Functional Partners:
dcn
Decorin; May affect the rate of fibrils formation. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 
 0.631
plod1a
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.
   
 0.628
col5a1
Procollagen, type V, alpha 1.
   
 
0.619
col6a2
Collagen, type VI, alpha 2.
   
0.616
col6a1
Collagen, type VI, alpha 1.
   
0.598
col1a1a
Collagen, type I, alpha 1a.
   
 
0.594
col11a1a
Collagen, type XI, alpha 1a.
   
 
0.570
plod2
Procollagen lysine 2-oxoglutarate 5-dioxygenase 2b isoform.
   
 0.556
ppib
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.552
col1a2
Collagen, type I, alpha 2.
   
 
0.548
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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