STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ssh1aSlingshot protein phosphatase 1a. (671 aa)    
Predicted Functional Partners:
cfl2
Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family.
    
 0.964
cfl1l
Cofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family.
    
 0.963
cfl1
Muscle cofilin 2; Belongs to the actin-binding proteins ADF family.
    
 0.963
ttll9
Tubulin tyrosine ligase-like family, member 9.
      
 0.743
limk1b
LIM domain kinase 1b.
   
 
 0.631
limk1a
LIM domain kinase 1a.
   
 
 0.594
coro1ca
Coronin-1C-A; Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (Probable). Increases the presence of activated RAC1 at the leading edge of migrating cells. Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments. Plays a role in endoplasmic reticulum-associated endosome fission: endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. [...]
 
 
 
 0.555
stt3a
STT3 oligosaccharyltransferase complex catalytic subunit A.
      
 0.544
limk2
LIM domain kinase 2.
   
 
 0.536
stt3b
STT3 oligosaccharyltransferase complex catalytic subunit B.
      
 0.515
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.