STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GANGigaxonin. (525 aa)    
Predicted Functional Partners:
tbcb
Tubulin folding cofactor B.
    
 
 0.878
map1b
Hypothetical microtubule-associated protein 1b.
    
 
 0.866
cul3b
Cullin 3b; Belongs to the cullin family.
    
 0.754
uba1
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
    
 
 0.638
UBE2M
Si:ch1073-205c8.3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.631
uba7
Ubiquitin-like modifier-activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
    
 
 0.620
cul3a
Cullin 3a; Belongs to the cullin family.
    
 
 0.607
uba3
NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric uba3-nae1 E1 enzyme. E1 activates nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a nedd8-uba3 thioester and free AMP. E1 finally transfers nedd8 to the catalytic cysteine of ube2m (By similarity).
     
 0.596
klhl3
Kelch-like protein 3; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron.
  
 
0.582
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.578
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.