STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pacsin3Protein kinase C and casein kinase substrate in neurons 3. (377 aa)    
Predicted Functional Partners:
camk2g2
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2.
   
  
 0.696
trpv4
Transient receptor potential cation channel, subfamily V, member 4.
      
 0.667
os9
OS9 endoplasmic reticulum lectin.
   
  
 0.648
fcho2
F-BAR domain only protein 2; May function in an early step of clathrin-mediated endocytosis.
     
 0.614
cnih4
Cornichon family AMPA receptor auxiliary protein 4.
      
 0.599
dnm2a
Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.595
cnih3
Cornichon family AMPA receptor auxiliary protein 3.
      
 0.591
chmp4ba
Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
    
 
 0.571
ttll11
Tubulin tyrosine ligase-like family, member 11.
      
 0.558
adam9
ADAM metallopeptidase domain 9.
    
 
 0.558
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.