STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itga4Integrin alpha 4; Belongs to the integrin alpha chain family. (1018 aa)    
Predicted Functional Partners:
vcam1b
Vascular cell adhesion molecule 1b.
   
 0.976
itgb7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.967
itgb1a
Integrin beta; Belongs to the integrin beta chain family.
   
 0.965
itgb1b
Integrin beta; Belongs to the integrin beta chain family.
   
 0.944
fn1a
Fibronectin 1a.
     
 0.923
itgb1b.2
Integrin beta; Belongs to the integrin beta chain family.
   
 0.918
itgb1b.1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.917
jam2b
Junctional adhesion molecule 2b.
     
  0.900
pxnb
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.849
pxna
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.849
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.