STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
creb1bcAMP-responsive element-binding protein 1b. (324 aa)    
Predicted Functional Partners:
rps6ka5
Ribosomal protein S6 kinase.
   
 0.810
klf7b
Kruppel-like factor 7 (Ubiquitous), like.
    
 
 0.806
rps6ka2
Ribosomal protein S6 kinase.
   
 0.789
rps6ka1
Ribosomal protein S6 kinase.
   
 0.789
mapkapk2a
Mitogen-activated protein kinase-activated protein kinase 2a; Belongs to the protein kinase superfamily.
   
 0.786
akt2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.777
akt3b
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.777
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.775
camkk1a
Calcium/calmodulin-dependent protein kinase kinase 1, alpha a; Belongs to the protein kinase superfamily.
   
  
 0.747
tbc1d23
TBC1 domain family member 23; Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (By similarity). Plays a role in brain development. May act as a general inhibitor of innate immunity signaling (By similarity).
      
 0.744
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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