STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprc5cG protein-coupled receptor, class C, group 5, member C. (429 aa)    
Predicted Functional Partners:
RNF157
Si:dkey-49c17.3.
    
 
 0.744
gpr52
G protein-coupled receptor 52; Belongs to the G-protein coupled receptor 1 family.
      
 0.669
vmn2r1
Vomeronasal 2, receptor 1.
      
 0.578
tmem150c
Transmembrane protein 150C.
      
 0.569
srp68
Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.
    
 
 0.567
col21a1
Collagen, type XXI, alpha 1.
    
 
 0.544
phka2
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.
      
 0.542
gpr4
G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family.
      
 0.539
gprc6a
G-protein coupled receptor family C group 6 member A; Olfactory receptor that is activated by amino acids that act as potent odorants in fish. Displays preference for acidic amino acids such as Glu over basic amino acids; Belongs to the G-protein coupled receptor 3 family.
      
 0.494
egfl6
EGF-like-domain, multiple 6.
    
 
 0.473
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.