STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSDARP00000137199Si:dkey-165o8.2. (1233 aa)    
Predicted Functional Partners:
chuk
Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
    
  0.533
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
  0.533
zgc:171776
Zgc:171776.
    
   0.480
adgrl2b.1
Adhesion G protein-coupled receptor L2b, tandem duplicate 1.
    
   0.480
zgc:171781
Zgc:171781.
    
   0.480
F1R0Z3_DANRE
Si:dkey-179j5.5.
    
   0.480
LOC110438301
Si:ch211-226h8.6.
    
   0.480
F1R862_DANRE
Si:ch211-226h8.4.
    
   0.480
A8HAI9_DANRE
Si:ch211-12h2.8.
    
   0.480
adgrl2b.1-2
Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.480
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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