STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chrnb4Cholinergic receptor, nicotinic, beta 4 (neuronal). (525 aa)    
Predicted Functional Partners:
chrna3
Cholinergic receptor, nicotinic, alpha 3.
  
  
0.935
chrna1
Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  
0.860
chrna5
Cholinergic receptor, nicotinic, alpha 5.
  
0.853
chrnb3b
Cholinergic receptor, nicotinic, beta polypeptide 3b.
  
0.853
chrna6
Cholinergic receptor, nicotinic, alpha 6.
  
  
0.808
chrna4b
Neuronal nicotinic acetylcholine receptor alpha 4 subunit.
  
 
0.803
chrna2a
Cholinergic receptor, nicotinic, alpha 2a (neuronal).
  
 
0.803
chrna7
Cholinergic receptor, nicotinic, alpha 7 (neuronal).
  
0.779
chrnb1
Cholinergic receptor, nicotinic, beta 1 (muscle).
  
  
0.735
chrng
Cholinergic receptor, nicotinic, gamma.
  
  
 
0.730
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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