STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plxna1aPlexin A1a. (1891 aa)    
Predicted Functional Partners:
nrp1a
Neuropilin-1a; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. Regulates angiogenesis through a VEGF-dependent pathway.
    
 0.951
sema3e
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family.
    
 
 0.816
sema6a
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A.
    
 
 0.811
sema3ab
Semaphorin-3ab; Might normally influence the midsegmental pathway choice of the ventrally extending motor axons by contributing to a repulsive domain in the posterior somite.
    
 0.773
sema3aa
Semaphorin-3aa; May influence outgrowth by a variety of growth cones including those of the posterior lateral line ganglion.
    
 
 0.772
plxnd1
Plexin D1.
     
0.728
sema6dl
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D,-like.
    
 0.720
sema3c
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C.
    
 
 0.700
sema7a
Semaphorin 7A; Belongs to the semaphorin family.
    
 
 0.695
sema6d
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Belongs to the semaphorin family.
    
 
0.674
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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