Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amotl1 | fat4 | ENSDARP00000024424 | ENSDARP00000147985 | Angiomotin_C domain-containing protein. | FAT atypical cadherin 4. | 0.732 |
| arfgef2 | fat4 | ENSDARP00000101022 | ENSDARP00000147985 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited). | FAT atypical cadherin 4. | 0.716 |
| ctnnb1 | fat4 | ENSDARP00000139205 | ENSDARP00000147985 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | FAT atypical cadherin 4. | 0.661 |
| ctnnb1 | invs | ENSDARP00000139205 | ENSDARP00000014904 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Inversin; Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. | 0.742 |
| ctnnb1 | prickle1a | ENSDARP00000139205 | ENSDARP00000059513 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Prickle homolog 1a. | 0.693 |
| ctnnb1 | vangl2 | ENSDARP00000139205 | ENSDARP00000031546 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...] | 0.769 |
| ctnnb1 | wnt9b | ENSDARP00000139205 | ENSDARP00000055224 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.767 |
| fat4 | amotl1 | ENSDARP00000147985 | ENSDARP00000024424 | FAT atypical cadherin 4. | Angiomotin_C domain-containing protein. | 0.732 |
| fat4 | arfgef2 | ENSDARP00000147985 | ENSDARP00000101022 | FAT atypical cadherin 4. | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited). | 0.716 |
| fat4 | ctnnb1 | ENSDARP00000147985 | ENSDARP00000139205 | FAT atypical cadherin 4. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.661 |
| fat4 | fjx1 | ENSDARP00000147985 | ENSDARP00000154085 | FAT atypical cadherin 4. | Four-jointed box kinase 1. | 0.868 |
| fat4 | invs | ENSDARP00000147985 | ENSDARP00000014904 | FAT atypical cadherin 4. | Inversin; Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. | 0.722 |
| fat4 | lix1l | ENSDARP00000147985 | ENSDARP00000115243 | FAT atypical cadherin 4. | Limb and CNS-expressed 1-like. | 0.585 |
| fat4 | prickle1a | ENSDARP00000147985 | ENSDARP00000059513 | FAT atypical cadherin 4. | Prickle homolog 1a. | 0.583 |
| fat4 | tyw3 | ENSDARP00000147985 | ENSDARP00000055736 | FAT atypical cadherin 4. | tRNA wybutosine-synthesizing protein 3 homolog; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). | 0.581 |
| fat4 | vangl2 | ENSDARP00000147985 | ENSDARP00000031546 | FAT atypical cadherin 4. | Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...] | 0.810 |
| fat4 | wnt9b | ENSDARP00000147985 | ENSDARP00000055224 | FAT atypical cadherin 4. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.667 |
| fjx1 | fat4 | ENSDARP00000154085 | ENSDARP00000147985 | Four-jointed box kinase 1. | FAT atypical cadherin 4. | 0.868 |
| fjx1 | prickle1a | ENSDARP00000154085 | ENSDARP00000059513 | Four-jointed box kinase 1. | Prickle homolog 1a. | 0.555 |
| fjx1 | vangl2 | ENSDARP00000154085 | ENSDARP00000031546 | Four-jointed box kinase 1. | Vang-like protein 2; Plays a role in non-canonical Wnt/planar cell polarity (PCP) signaling to regulate convergent extension cell movements during gastrulation. Acts together with scrib and prickle1 and localizes prickle1 and dvl2/dsh to the plasma membrane. Has an overlapping role with kny during both convergent extension and eye development. In the eye, involved in establishing proper alignment of the anterior neural plate and midline cells expressing shha and shhb/twhh. Has indirect effects on a number of other developmental processes including notochord shape formation, neural prog [...] | 0.667 |
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