STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pmtPhosphoethanolamine methyltransferase. (498 aa)    
Predicted Functional Partners:
cyp51
Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
   
 
 0.991
sc5d
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.990
sigmar1
Sigma non-opioid intracellular receptor 1; May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. May regulate calcium efflux at the endoplasmic reticulum (By similarity).
   
 0.985
lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.979
hsd17b7
Hydroxysteroid (17-beta) dehydrogenase 7.
   
 
 0.977
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
   
 
 0.976
ERG28
Ergosterol biosynthesis 28 homolog.
    
 
 0.975
pcyt1ba
Phosphate cytidylyltransferase 1, choline, beta a.
  
 
 0.973
chkb
Choline kinase beta.
    
 0.949
pcyt1bb
Phosphate cytidylyltransferase 1, choline, beta b.
  
 
 0.944
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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