node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cmpk | hmgb2b | ENSDARP00000008412 | ENSDARP00000153222 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | High mobility group box 2b. | 0.560 |
h2az2a | hmgb2b | ENSDARP00000090434 | ENSDARP00000153222 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | High mobility group box 2b. | 0.511 |
h2az2b | hmgb2b | ENSDARP00000154835 | ENSDARP00000153222 | Histone H2A; Belongs to the histone H2A family. | High mobility group box 2b. | 0.540 |
hmgb2b | cmpk | ENSDARP00000153222 | ENSDARP00000008412 | High mobility group box 2b. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.560 |
hmgb2b | h2az2a | ENSDARP00000153222 | ENSDARP00000090434 | High mobility group box 2b. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.511 |
hmgb2b | h2az2b | ENSDARP00000153222 | ENSDARP00000154835 | High mobility group box 2b. | Histone H2A; Belongs to the histone H2A family. | 0.540 |
hmgb2b | mxg | ENSDARP00000153222 | ENSDARP00000095115 | High mobility group box 2b. | Myxovirus (influenza virus) resistance G; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.523 |
hmgb2b | nt5dc3 | ENSDARP00000153222 | ENSDARP00000085982 | High mobility group box 2b. | 5'-nucleotidase domain-containing 3. | 0.620 |
hmgb2b | purab | ENSDARP00000153222 | ENSDARP00000130277 | High mobility group box 2b. | Purine-rich element-binding protein Ab. | 0.573 |
hmgb2b | rsf1b.1 | ENSDARP00000153222 | ENSDARP00000071629 | High mobility group box 2b. | Remodeling and spacing factor 1b, tandem duplicate 1. | 0.590 |
hmgb2b | snrpb2 | ENSDARP00000153222 | ENSDARP00000057600 | High mobility group box 2b. | Small nuclear ribonucleoprotein polypeptide B2. | 0.506 |
hmgb2b | srsf3a | ENSDARP00000153222 | ENSDARP00000035207 | High mobility group box 2b. | Serine and arginine-rich-splicing factor 3a. | 0.491 |
hmgb2b | tp53 | ENSDARP00000153222 | ENSDARP00000116736 | High mobility group box 2b. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.556 |
mxg | hmgb2b | ENSDARP00000095115 | ENSDARP00000153222 | Myxovirus (influenza virus) resistance G; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | High mobility group box 2b. | 0.523 |
nt5dc3 | hmgb2b | ENSDARP00000085982 | ENSDARP00000153222 | 5'-nucleotidase domain-containing 3. | High mobility group box 2b. | 0.620 |
nt5dc3 | purab | ENSDARP00000085982 | ENSDARP00000130277 | 5'-nucleotidase domain-containing 3. | Purine-rich element-binding protein Ab. | 0.836 |
purab | hmgb2b | ENSDARP00000130277 | ENSDARP00000153222 | Purine-rich element-binding protein Ab. | High mobility group box 2b. | 0.573 |
purab | nt5dc3 | ENSDARP00000130277 | ENSDARP00000085982 | Purine-rich element-binding protein Ab. | 5'-nucleotidase domain-containing 3. | 0.836 |
rsf1b.1 | hmgb2b | ENSDARP00000071629 | ENSDARP00000153222 | Remodeling and spacing factor 1b, tandem duplicate 1. | High mobility group box 2b. | 0.590 |
rsf1b.1 | snrpb2 | ENSDARP00000071629 | ENSDARP00000057600 | Remodeling and spacing factor 1b, tandem duplicate 1. | Small nuclear ribonucleoprotein polypeptide B2. | 0.768 |