STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSDARP00000154441SEFIR domain-containing protein. (768 aa)    
Predicted Functional Partners:
il17a/f1
Interleukin 17a/f1.
    
 
 0.870
wu:fl23c11
SEFIR domain-containing protein.
    
 
 0.772
traf3ip2l
TRAF3-interacting protein 2-like.
    
 
 0.625
Traf3ip2b
SEFIR domain-containing protein.
    
 
 0.625
il17c
Interleukin 17_3.
    
 
 0.526
traf6
TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.
   
 
 0.471
cd4-1
CD4-1 molecule.
      
 0.471
il17d
Interleukin 17_4.
    
 
 0.430
il17a/f3
Interleukin 17a/f3.
    
 
 0.430
il17a/f2
Interleukin 17a/f2.
    
 
 0.430
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.