STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parp6bPoly [ADP-ribose] polymerase. (645 aa)    
Predicted Functional Partners:
rpl11
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
  
 
 0.827
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
  
 
 0.825
rps15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 0.824
pgk1
Phosphoglycerate kinase.
  
 0.806
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.805
rpl23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
   0.789
rpl32
Ribosomal protein L32.
  
   0.788
rps4x
40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family.
  
   0.783
rpl35
60S ribosomal protein L35; Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. Belongs to the universal ribosomal protein uL29 family.
  
   0.782
rpl15
Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.
   
 
 0.773
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.