STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfge8aMilk fat globule-EGF factor 8 protein a. (478 aa)    
Predicted Functional Partners:
hmgb2a
High mobility group box 2a.
    
 
 0.582
ano6
Anoctamin.
      
 0.563
nusap1
Nucleolar and spindle-associated protein 1; Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them (By similarity).
      
 0.561
fam20cb
FAM20C golgi-associated secretory pathway kinase b.
    
  0.525
mcm2
DNA helicase; Belongs to the MCM family.
    
 
 0.517
col4a5
Collagen, type IV, alpha 5 (Alport syndrome).
    
 
 0.501
insm1a
Insulinoma-associated protein 1a; May act as a transcriptional regulator. May play a role in neurogenesis and neuroendocrine cell differentiation during embryonic development (By similarity).
      
 0.453
klf6a
Kruppel-like factor 6a.
    
 
 0.428
hephl1a
Hephaestin-like 1a; Belongs to the multicopper oxidase family.
 
  
 
 0.419
cp
Ceruloplasmin; Belongs to the multicopper oxidase family.
 
  
 
 0.414
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]