STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (223 aa)    
Predicted Functional Partners:
pyrF
Protein involved in orotidine-5'-phosphate decarboxylase activity and 'de novo' pyrimidine base biosynthetic process; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
 
 0.998
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.989
MW7_0714
Protein involved in aspartate carbamoyltransferase activity and pyrimidine base metabolic process.
  
 
 0.972
carB
Protein involved in carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity and pyrimidine base metabolic process; Belongs to the CarB family.
  
 
 0.962
pyrR
PyrR bifunctional protein: Pyrimidine operon regulatory protein; Protein involved in uracil phosphoribosyltransferase activity and pyrimidine base metabolic process.
  
 
 0.955
pyrB
Protein involved in aspartate carbamoyltransferase activity and 'de novo' pyrimidine base biosynthetic process; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.953
carA
Protein involved in carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity and pyrimidine base metabolic process; Belongs to the CarA family.
  
  
 0.945
MW7_2006
Methanesulfonate monooxygenase component; Protein involved in electron carrier activity and electron transport.
  
 
 0.932
MW7_2345
Methanesulfonate monooxygenase component; Protein involved in electron carrier activity and electron transport.
  
 
 0.932
MW7_2548
Cdp-6-deoxy-delta- -glucoseen reductase; Protein involved in ferredoxin-NAD+ reductase activity and electron transport.
  
 
 0.932
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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