Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MW7_03663-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase); Protein involved in 3-deoxy-manno-octulosonate-8-phosphatase activity and lipopolysaccharide biosynthetic process. (201 aa)    
Predicted Functional Partners:
MW7_0367
Arabinose-5-phosphate isomerase; Protein involved in protein binding and carbohydrate metabolic process; Belongs to the SIS family. GutQ/KpsF subfamily.
 
 0.999
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
 0.994
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Protein involved in 3-deoxy-8-phosphooctulonate synthase activity and lipopolysaccharide biosynthetic process; Belongs to the KdsA family.
  
 0.992
lptC
Hypothetical protein.
  
  
 0.867
MW7_0750
3-deoxy-d-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.855
lptB
ABC transporter ATP-binding protein; Protein involved in ATP binding and amino acid transport.
 
  
 0.809
lptA
OstA-like protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
  
  
 0.747
lpxA
Udp-n-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.726
lpxC
UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.723
MW7_0368
Kef-type k+ transport membrane and nad-binding component; Protein involved in nucleotide binding and potassium ion transport; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
       0.703
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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