Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MW7_0899Glycine cleavage T-protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. (370 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 0.999
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.998
MW7_0902
Hypothetical protein.
   
 0.949
lpdA
Protein involved in dihydrolipoyl dehydrogenase activity and gluconeogenesis.
 
 0.930
MW7_0901
Ferredoxin; Protein involved in electron carrier activity and electron transport.
 
 
 0.910
putA
Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.882
MW7_0900
Hypothetical protein.
 
   
 0.881
MW7_2515
Protein involved in sarcosine oxidase activity and glycine metabolic process.
 0.878
MW7_1865
Transketolase; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor and metabolic process.
     
 0.875
MW7_3281
Glutamate synthase, large subunit; Protein involved in glutamate synthase (NADPH) activity and electron transport.
    
 0.866
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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