Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (383 aa)    
Predicted Functional Partners:
MW7_1991
Protein involved in succinyldiaminopimelate transaminase activity and lysine biosynthetic process via diaminopimelate.
 
  
 0.953
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.944
prmB
Putative adenine-specific methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
 
    0.906
argG
Protein involved in argininosuccinate synthase activity and alanine metabolic process; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.849
argD
Acetylornithine transaminase; Protein involved in N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity and urea cycle intermediate metabolic process; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.847
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.823
argA
N-acetylglutamate synthase; Protein involved in acetyl-CoA:L-glutamate N-acetyltransferase activity and urea cycle intermediate metabolic process; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.817
argE
Acetylornithine deacetylase; Protein involved in protein binding and urea cycle intermediate metabolic process.
  
  
0.808
dapD
Protein involved in 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity and diaminopimelate biosynthetic process; Belongs to the transferase hexapeptide repeat family.
 
   
 0.805
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.789
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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