STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MW7_2309Redox protein regulator of disulfide-bond formation; Protein involved in response to stress. (140 aa)    
Predicted Functional Partners:
lpdA
Protein involved in dihydrolipoyl dehydrogenase activity and gluconeogenesis.
    
 0.722
ffh
Ffh protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to the GTP-b [...]
   
    0.694
MW7_1865
Transketolase; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor and metabolic process.
    
  0.674
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
  0.525
cysM
Protein involved in cysteine synthase activity and cysteine biosynthetic process from serine; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
   
 0.493
MW7_1540
AMP-dependent synthetase and ligase; Protein involved in catalytic activity and metabolic process.
    
  0.413
MW7_0026
Glutathione reductase gor; Protein involved in oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor and cell redox homeostasis.
    
 0.405
MW7_0806
Protein involved in dihydrolipoyl dehydrogenase activity and gluconeogenesis.
    
 0.405
lpdA-2
Protein involved in dihydrolipoyl dehydrogenase activity and gluconeogenesis.
    
 0.405
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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