STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpSATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (108 aa)    
Predicted Functional Partners:
clpA
ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Protein involved in ATP-dependent peptidase activity and ATP-dependent proteolysis; Belongs to the ClpA/ClpB family.
 
 0.994
putA
Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
 
 
   0.938
MW7_2394
DNA-binding ferritin-like protein; Protein involved in DNA binding and cellular iron ion homeostasis; Belongs to the Dps family.
   
 
 0.932
clpK
ATP-dependent Clp protease, ATP-binding subunit ClpC; Protein involved in protein binding and auxin biosynthetic process; Belongs to the ClpA/ClpB family.
  
 
 0.915
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.915
aat
Aat protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
 
  
 0.821
ihfA
Integration host factor (IHF), alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
    0.690
MW7_1832
Putative ATP-dependent helicase; Protein involved in DNA binding and nucleobase, nucleoside, nucleotide and nucleic acid metabolic process.
      0.678
MW7_1610
Peptidase S14 ClpP; Protein involved in serine-type endopeptidase activity and proteolysis; Belongs to the peptidase S14 family.
   
 
 0.563
clpP
ClpP protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.563
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.