node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MW7_1102 | aroA | MW7_1102 | MW7_1103 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.997 |
MW7_1102 | aroB | MW7_1102 | MW7_3278 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.789 |
MW7_1102 | aroC | MW7_1102 | MW7_1740 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.952 |
MW7_1102 | aroE | MW7_1102 | MW7_3165 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.437 |
MW7_1102 | aroG | MW7_1102 | MW7_2722 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.564 |
MW7_1102 | aroK | MW7_1102 | MW7_3277 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | AroK protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.792 |
MW7_1102 | pheA | MW7_1102 | MW7_1100 | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | Protein involved in chorismate mutase activity and tryptophan biosynthetic process. | 0.966 |
MW7_3279 | aroB | MW7_3279 | MW7_3278 | Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Protein involved in magnesium ion binding and purine base metabolic process; Belongs to the dGTPase family. Type 2 subfamily. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.740 |
MW7_3279 | aroK | MW7_3279 | MW7_3277 | Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Protein involved in magnesium ion binding and purine base metabolic process; Belongs to the dGTPase family. Type 2 subfamily. | AroK protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.740 |
aroA | MW7_1102 | MW7_1103 | MW7_1102 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | 0.997 |
aroA | aroB | MW7_1103 | MW7_3278 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.995 |
aroA | aroC | MW7_1103 | MW7_1740 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.998 |
aroA | aroE | MW7_1103 | MW7_3165 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.995 |
aroA | aroK | MW7_1103 | MW7_3277 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | AroK protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.985 |
aroA | aroQ | MW7_1103 | MW7_2424 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.572 |
aroA | aroQ-2 | MW7_1103 | MW7_3173 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.572 |
aroA | pheA | MW7_1103 | MW7_1100 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Protein involved in chorismate mutase activity and tryptophan biosynthetic process. | 0.987 |
aroB | MW7_1102 | MW7_3278 | MW7_1102 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Prephenate dehydrogenase TyrA; Protein involved in nucleotide binding and tryptophan biosynthetic process. | 0.789 |
aroB | MW7_3279 | MW7_3278 | MW7_3279 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Protein involved in magnesium ion binding and purine base metabolic process; Belongs to the dGTPase family. Type 2 subfamily. | 0.740 |
aroB | aroA | MW7_3278 | MW7_1103 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.995 |