STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANE23417.1Cu2+-exporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (765 aa)    
Predicted Functional Partners:
ANE23473.1
Zinc ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.777
ANE22553.1
Cadmium ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.723
ANE22552.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.700
ANE22835.1
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
   0.700
ANE22513.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
 
  
 0.610
ANE21919.1
2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.554
ANE22931.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.541
ANE23347.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.541
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
 
   
 0.512
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 
 0.496
Your Current Organism:
Denitrobacterium detoxificans
NCBI taxonomy Id: 79604
Other names: ATCC 700546, CCUG 56741, D. detoxificans, DSM 21843, Denitrobacterium detoxificans Anderson et al. 2000, nitropropanol-degrading bacterium NPOH1, strain NPOH1
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