STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gen1GEN1 Holliday junction 5' flap endonuclease. (905 aa)    
Predicted Functional Partners:
Wrn
WRN RecQ like helicase.
  
 0.999
Pcna
Proliferating cell nuclear antigen.
  
 0.975
Mre11
MRE11 homolog, double strand break repair nuclease.
  
 0.947
Gtf2h1
General transcription factor IIH subunit 1.
    
 0.945
Dna2
DNA replication helicase/nuclease 2.
   
 0.937
Fancm
FA complementation group M.
   
 0.927
Pold2
DNA polymerase delta 2, accessory subunit.
  
 0.915
Ercc3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.914
Blm
Bloom syndrome, RecQ like helicase.
  
 0.889
Mus81
MUS81 structure-specific endonuclease subunit.
   
 0.882
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.