STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PtenPhosphatase and tensin homolog. (403 aa)    
Predicted Functional Partners:
Trp53
Tumor protein p53.
   
 0.981
Ptk2
Protein tyrosine kinase 2.
    
 0.981
Wwp2
WW domain containing E3 ubiquitin protein ligase 2.
    
 0.971
Nedd4
NEDD4 E3 ubiquitin protein ligase.
    
 0.970
Usp7
Ubiquitin specific peptidase 7.
   
 0.969
Mast2
Microtubule associated serine/threonine kinase 2.
    
 
 0.960
Magi2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
 0.960
Pik3r1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.959
Pik3ca
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.954
Pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.
    
 0.939
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.