STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pik3r1Phosphoinositide-3-kinase regulatory subunit 1. (723 aa)    
Predicted Functional Partners:
Pik3ca
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.997
Pik3cd
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
    
 0.996
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.994
Egfr
Epidermal growth factor receptor.
    
 0.993
Cbl
Cbl proto-oncogene.
    
 0.993
Pdgfrb
Platelet derived growth factor receptor, beta polypeptide.
    
 0.993
Irs1
Insulin receptor substrate 1.
    
 0.993
ENSMOCP00000022792
annotation not available
    
0.992
Erbb3
Erb-b2 receptor tyrosine kinase 3.
    
 0.991
Kit
KIT proto-oncogene, receptor tyrosine kinase.
    
 0.989
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.