STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Frs3Fibroblast growth factor receptor substrate 3. (492 aa)    
Predicted Functional Partners:
Grb2
Growth factor receptor bound protein 2.
    
 0.975
Alk
ALK receptor tyrosine kinase.
    
 0.944
Ptpn11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.944
Fgfr1
Fibroblast growth factor receptor 1.
    
 0.914
Fgfr2
Fibroblast growth factor receptor 2.
    
 0.902
Fgfr3
Fibroblast growth factor receptor 3.
    
 0.893
Fgfr4
Fibroblast growth factor receptor 4.
    
 0.893
Ret
Ret proto-oncogene.
    
 0.878
Ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.877
Stil
STIL centriolar assembly protein.
    
 0.859
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.