STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hmgcr3-hydroxy-3-methylglutaryl-CoA reductase. (887 aa)    
Predicted Functional Partners:
Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
  
 
 0.995
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2.
  
 
 0.993
Mvk
Mevalonate kinase.
  
 0.958
Ubiad1
UbiA prenyltransferase domain containing 1.
   
 
 0.955
Mvd
Mevalonate diphosphate decarboxylase.
  
 
 0.955
Sqle
Squalene epoxidase.
  
  
 0.951
Insig1
Insulin induced gene 1.
   
 
 0.948
Cyp51
Lanosterol 14-alpha demethylase.
  
  
 0.945
Insig2
Insulin induced gene 2.
   
 
 0.943
Amfr
Autocrine motility factor receptor.
   
 
 0.909
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.