STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smurf1SMAD specific E3 ubiquitin protein ligase 1. (757 aa)    
Predicted Functional Partners:
Smad7
SMAD family member 7.
    
 0.996
Smad6
SMAD family member 6.
    
 0.992
Smad1
SMAD family member 1.
    
 0.988
Smurf2
SMAD specific E3 ubiquitin protein ligase 2.
  
0.979
Smad5
SMAD family member 5.
    
 0.975
LOC101978981
Ubiquitin-like.
    
 0.956
Tgfbr1
Transforming growth factor beta receptor 1.
    
 0.939
Smad2
SMAD family member 2.
    
 0.933
Tgfbr2
Transforming growth factor beta receptor 2.
    
 0.931
Ptch2
Patched 2.
    
 0.918
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.