STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cd80CD80 antigen. (298 aa)    
Predicted Functional Partners:
Ctla4
Cytotoxic T-lymphocyte associated protein 4.
   
 0.996
Cd28
CD28 molecule.
   
 0.991
Cd86
CD86 antigen.
   
0.979
Cd274
CD274 molecule.
   
0.955
Pdcd1lg2
Programmed cell death 1 ligand 2.
   
 0.946
Cd40
CD40 molecule.
   
 
 0.835
Cd4
CD4 molecule.
   
 0.818
Ptpn11
Protein tyrosine phosphatase non-receptor type 11.
   
 0.786
B2m
Beta-2-microglobulin.
   
 0.776
Lck
LCK proto-oncogene, Src family tyrosine kinase.
   
 0.772
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.