STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Git1GIT ArfGAP 1. (756 aa)    
Predicted Functional Partners:
Pxn
Paxillin.
    
 0.993
Arhgef7
Rho guanine nucleotide exchange factor 7.
    
 0.988
Lpxn
Leupaxin.
    
 0.988
Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.982
Itsn2
Intersectin 2.
   
 
 0.980
Git2
GIT ArfGAP 2.
  
 
0.932
Tgfb1i1
Transforming growth factor beta 1 induced transcript 1.
    
 0.930
Cdc42
Cell division cycle 42.
    
 0.915
Pak2
P21 (RAC1) activated kinase 2.
    
 0.905
Ppfia1
PTPRF interacting protein alpha 1.
    
 
 0.887
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.